GEN-TEC NUTRACEUTICALS source, blend and package 100% pure pharmaceutical grade ARGININE ALPHA KETOGLUTERATE powder. ARGININE ALPHA KETOGLUTERATE supplementation is ideal for individuals with a goal of increasing endogenous Nitric Oxide levels. ARGININE is a conditionally essential amino acid for individuals engaging in intensive exercise as it supports endogenous production of Creatine Phosphate.
SUGGESTED USE: Mix 1g (1/4 tsp) of ARGININE AKG in 150mL water and consume 20 minutes before exercise. Store in a cool, dry, dark place.
INGREDIENTS: Pharmaceutical grade ARGININE ALPHA KETOGLUTERATE.
May contain traces of milk, soybeans, cereals containing gluten, tree nuts, sesame seeds and their products.
DISCLAIMER: Formulated Supplementary Sports Food. This product is not a sole source of nutrition and should be consumed in conjunction with a nutritious diet and an appropriate physical training or exercise program. Not suitable for children under 15 years of age or pregnant women. Should only be used under medical or dietetic supervision.
Made in Australia from local and imported ingredients.
Vasodilation, Nitric Oxide Production, Creatine Synthesis, Connective Tissue
support, Growth Hormone support.
Arginine (Arg) is classified as a conditionally essential amino acid. This means
under times of intense stress, illness or trauma the body requires more than
what it can make(Botchlett et al., 2013). Arginine alpha-ketogluterate (AAKG) is
a derivative of arginine that increase’s nitric oxide production more effectively.
The benefits of increased NO production is an increase in vasodilation which
increases the diameter of blood vessels (hoses). This in turn leads to an increase
in blood flow by relaxing the vascular cells (bigger pipes) which leads to greater
oxygen and nutrient transportation. Clinically, AAKG and Arg has been used
to treat patients with cardiovascular problems and erectile dysfunction as the
vasodilatory properties of Arg improve blood flow, regulate inflammation and
can reduce proteins sticking the blood vessel walls, thus smoother flow of blood
(Campbell et al., 2006). Furthermore, Arginine is also converted to Ornithine
which is an amino acid that works with Proline to improve collagen production
(healthy joints) and wound healing (Arthur, 2009).
Moreover, in exercising individuals Arginine is involved in the synthesis of
Creatine which is an amino acid that increases strength and performance by
up to 15% in most athletes. As Creatine is heavily used during high intensity
exercises, the demand on creatine synthesis is much greater, therefore the
supplementation of Arg will support continual production to meet demands. In
addition, Arg supplementation during exercise leads to venous pooling (a pump).
This sensation of a “pump” is heightened due to the improvement in blood vessel
size. Moreover, the effects arginine has on growth hormone release has been
documented in various population groups with the overall consensus being that
arginine stimulates the posterior pituitary gland to release growth hormone,
which may be of benefit for recovery and body composition depending on the
individual (Crowe et al., 2006, Collier et al., 2005).
A further crucial role that Arg plays in both health and in performance is its
ability to firstly scavenge free radicals (eliminate bad toxins) and remove waste
products that are metabolically created through intense exercise. Therefore the
more arginine there is (within limits) the better your body can remove excess
waste products, improve nutrient delivery and improve vascular function (Collier
et al., 2005, Arthur, 2009)
ARTHUR, R. 2009. Amino Acids. Journal of Complementary Medicine: CM, The,
BOTCHLETT, R., LAWLER, J. M. & WU, G. 2013. Chapter 45 – L-Arginine and
L-Citrulline in Sports Nutrition and Health. In: BAGCHI, D., NAIR, S. & SEN, C. K.
(eds.) Nutrition and Enhanced Sports Performance. San Diego: Academic Press.
CAMPBELL, B., ROBERTS, M., KERKSICK, C., WILBORN, C., MARCELLO, B.,
TAYLOR, L., NASSAR, E., LEUTHOLTZ, B., BOWDEN, R., RASMUSSEN, C.,
GREENWOOD, M. & KREIDER, R. 2006. Pharmacokinetics, safety, and effects on
exercise performance of L-arginine alpha-ketoglutarate in trained adult men.
Nutrition (Burbank, Los Angeles County, Calif.), 22, 872-81.
COLLIER, S. R., CASEY, D. P. & KANALEY, J. A. 2005. Growth hormone responses
to varying doses of oral arginine. Growth Hormone & IGF Research, 15, 136-139.
CROWE, M. J., WEATHERSON, J. N. & BOWDEN, B. F. 2006. Effects of dietary
leucine supplementation on exercise performance. European Journal of Applied
Physiology, 97, 664-72.